JN1209型重组小鼠SHH(C25II)促销

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JN1209型重组小鼠SHH(C25II)促销是高品质的重组蛋白产品，由北京百奥莱博供应，用于科研实验，本产品质量好，且极具价格优势，深为用户称道，了解更多重组小鼠SHH(C25II)等重组蛋白产品请联*(代"系")我司咨询订购。

名称：JN1209型重组小鼠SHH(C25II)促销
编号：JN1209
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse Sonic Hedgehog
品Pai：百奥莱博
产地：北京
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Cys25-Gly198(Cys25Ile-Ile)表达纯化得来。

SHH(C25II)质量控制：＞95%(还原性SDS-PAGE)

SHH(C25II)制剂：冻干品

SHH(C25II)保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

SHH(C25II)复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于SHH(C25II)：
Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N­terminal fragment (Shh­N), and a catalytic­processing,glycosylated, 34 kDa, 239 aa C­terminal fragment. The 20 kDa Shh­N fragment is the core of the active hedgehog molecule. Mouse Shh­N is 99%, 98%, and aa identical to human, rat and gerbil Shh­N, respectively.

JN1209型重组小鼠SHH(C25II)促销正在火爆，除此之外，为您推荐下别产品：

·重组食蟹猴细胞程序死亡蛋白1(PD-1)
编号：JN1539
英文名称：Recombinant Cynomolgus monkey Programmed Cell Death Protein 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Pro21-Gln167在C端含有His标签。

PD-1质量控制：＞95%(还原性SDS-PAGE)

PD-1制剂：冻干品

PD-1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PD-1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PD-1：
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.


JN1209型重组小鼠SHH(C25II)促销关键词：JN1209,重组小鼠SHH,重组小鼠C25II,重组SHH,重组小鼠SHH蛋白


·重组人精*琥珀酸合成酶(ASS1)
编号：JN0721
英文名称：Recombinant Human Argininosuccinate Synthase
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Lys412在N端含有His标签。

ASS1质量控制：＞95%(还原性SDS-PAGE)

ASS1制剂：液体

ASS1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于ASS1：
Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.


JN1209型重组小鼠SHH(C25II)促销关键词：JN1209,重组小鼠SHH,重组小鼠C25II,重组SHH,重组小鼠SHH蛋白


·重组人Serpin A3(丝*酸蛋白酶YZ剂A3)
编号：JN1702
英文名称：Recombinant Human Serine Protease Inhibitor-clade A3
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的His24-Ala423在C端含有His标签。

Serpin A3质量控制：＞95%(还原性SDS-PAGE)

Serpin A3制剂：冻干品

Serpin A3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Serpin A3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Serpin A3：
Serpin A3 belongs to the Serpin superfamily of serine protease inhibitors. Serpin A3 has been shown to inhibit some serine proteases, such as neutrophil cathepsin G and mast cell chymase. Serpin A3 is synthesized initially in the liver and secreted in plasma. Serpin A3 has been found in the amyloid plaques from the hippocampus of Alzheimer disease brains. In addition to, Serpin A3 is associated with liver disease and Parkinson disease and chronic obstructive pulmonary disease.

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