特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
北京百奥莱博主要从事生物试剂的生产和销*(代"售"),产品线涵盖重组小鼠CCL3(MIP-1a) 重组蛋白在内的分子生物学试剂产品,还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。
名称:重组小鼠CCL3(MIP-1a) 重组蛋白
编号:JN1604
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Mouse C-C Motif Chemokine 3
品Pai:百奥莱博
产地:北京
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Ala24-Ala92在N端含有His标签。
CCL3/MIP-1a质量控制:>95%(还原性SDS-PAGE)
CCL3/MIP-1a制剂:冻干品
CCL3/MIP-1a保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
CCL3/MIP-1a复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于CCL3/MIP-1a:
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. Mature mouse CCL3 shares 73%, 91%, and 82% amino acid sequence identity with human, rat, and cotton rat CCL3, respectively. CCL3 exerts its biological functions through interactions with CCR1, CCR3, and CCR5. It is cleared from the extracellular space by internalization via the decoy chemokine receptor D6. CCL3 promotes the chemoattraction, adhesion to activated vascular endothelium, and cellular activation of many hematopoietic cell types including activated T cells, NK cells, neutrophils, monocytes, immature dendritic cells, and eosinophils. CCL3 is also known as stem cell inhibitor (SCI) and can inhibit the proliferation of hematopoietic progenitor cells. CCL3 bioactivity contributes to tumor metastasis and the inflammatory components of viral infection, rheumatoid arthritis, and hepatitis, although it also can suppress the replication of HIV.
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更多有关重组小鼠CCL3(MIP-1a) 重组蛋白的价格及使用说明等,请联*(代"系")我们的业务经理王欣女士咨询,我公司还销*(代"售")以下产品:
KFS087 4-20%预制胶(205-6.5 kDa分离范围;15个样/胶)
BTN160697 1×TBS(含5%BSA,0.1%Tween20溶液)
SY0112 STAT5-Luc荧光素酶报告基因质粒 STAT5 luciferase reporter plasmid
BTN120504 柱式藻类RNA大量提取试剂盒 Algae RNA Column large-scale extraction kit
WE0140 实时荧光定量PCR预混体系(SYBR GreenⅠ) BaReSYBR Mixture
SV0429 Hpy166II限制性内切酶 Hpy166II Restriction Endonuclease
SV1616 ACP 合成酶
BTN70905 2%明胶溶液(PCR级) Gelatin Solution,PCR Grade
YT149 罗丹明123 Rhodamine 123
SV1303 1 kb DNA Ladder
HR0315 磷酸酶YZ剂混合物片剂 Phosphatase inhibitor mixture tablet
BTN100214 预混型BCIP/NBT溶液 Premixed BCIP/NBT Solution
YT562 天冬*酸转*酶 Aspartate Transaminase (Crude Enzyme)
ALH190 miRNA荧光定量PCR检测试剂盒 miRNA fluorescent quantitative PCR detection kit
KFS190 Annexin V-APC/7-AAD双染细胞凋亡检测试剂盒 Annexin V-APC/7-AAD Apoptosis Detection Kit
RFT154 2×Tricine上样缓冲液(还原,2×) 2×Tricine Loading Buffer (reducing,2×)
SY0216 FXR-GFP报告基因质粒 FXR GFP Reporter Plasmid
重组小鼠CCL3(MIP-1a) 重组蛋白关键词:重组小鼠CCL3蛋白,重组CCL3,JN1604,重组小鼠MIP-1a
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SV0723 SphI-HF限制性内切酶 SphI-HF Restriction Endonuclease
SY0581 细胞衰老β-半乳糖苷酶染色试剂盒 Cell Senescence β-Galactosidase Staining Kit
BTN130560 大肠杆菌Rosetta-gami (DE3)pLys化学感受态细胞 E.coli Rosetta-gami (DE3)pLys Chemical Competent Cell
YT256 STAT3凝胶迁移突变探针(1.75μM) STAT3 Mutation Probe For EMSA(1.75μM)
SV1470 SHuffle T7 表达 E. coli 感受态细胞
BTN80204 柱式RNA纯化试剂盒 RNAadsorp RNA Column Purification Kit
BTN120511 CpG甲基转移酶(M.SssI) CpG Methyltransferase(M.SssI)
YT911 苏木素染色液 Hematoxylin Staining Solution
HR0121 神经元蛋白提取试剂盒 Neuron protein extraction kit
KFS293 Cisplatin (DNA交联剂/细胞凋亡诱导剂) Cisplatin
SV0033 AhdI限制性内切酶 AhdI Restriction Endonuclease
SY0320 10×RIPA裂解液(中)(不含蛋白酶磷酸酶YZ剂) 10×RIPA Lysis Buffer (Medium),without enzyme inhibitors
KFS092 1×电转移缓冲液
YT007 RNase A (10mg/ml) Ribonuclease A
重组小鼠CCL3(MIP-1a) 重组蛋白关键词:重组小鼠CCL3蛋白,重组CCL3,JN1604,重组小鼠MIP-1a
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·重组人FcγRIIB
编号:JN0568
英文名称:Recombinant Human Low Affinity Immunoglobulin Gamma Fc Region Receptor II-B
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Thr43-Pro217在C端含有His标签。
FcγRIIB质量控制:>95%(还原性SDS-PAGE)
FcγRIIB制剂:冻干品
FcγRIIB保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
FcγRIIB复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于FcγRIIB:
FcγRIIB is a low affinity receptor that recognizes the Fc portion of IgG. The human CD32 group consists of FcγRIIA, FcγRIIB, and FcγRIIC proteins that share 94-99% sequence identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. FcγRII protein is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. FcγRIIB has an intrinsic cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM) and delivers an inhibitory signal upon ligand binding. Ligation of FcγRIIB on B cells down-regulates antibody production and in some circumstances may promote apoptosis. Co-ligation of FcγRIIB on dendritic cells inhibits maturation and blocks cell activation. FcγRIIB may also be a target for monoclonal antibody therapy for malignancies. FcγRIIB plays an important negative-regulating role through modulating the signals from activation receptors.
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