重组小鼠PD-L2(B7-DC) 重组蛋白

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、YL及其他非科研用途。

北京百奥莱博专业生产销*(代"售")重组小鼠PD-L2(B7-DC) 重组蛋白，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组小鼠PD-L2(B7-DC) 重组蛋白
编号：JN1896
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse Programmed Cell Death 1 Ligand 2
品Pai：百奥莱博
产地：北京
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu20-Arg219在C端带有Fc标签。

PD-L2/B7-DC质量控制：＞95%(还原性SDS-PAGE)

PD-L2/B7-DC制剂：冻干品

PD-L2/B7-DC保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PD-L2/B7-DC复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PD-L2/B7-DC：
Programmed cell death 1 ligand 2 (PD-L2),also known as butyrophilin B7-DC or PDCD1 ligand 2, belongs to the member of B7 family which can regulate the activation and tolerance ofT cells. PD-L2 is one ligand for Programmed cell death 1(PD-1), and the other is PD-L1. These two ligands shares 34% aa sequence identity. Mouse PD-L2 gene encodes a 273 amino acids (aa) protein with a putative 19 aa signal peptide, a 201 aa extracellular region , a 21 aa transmembrane domain and a 32 aa cytoplasmic region. The mouse PD-L2 gene is highly expressed in heart, placenta, pancreas, lung and liver while expressed weakly in spleen, lymph nodes and thymus. Besides, the expression of PD-L2 gene can be induced on dendritic cells grown from peripheral blood mononuclear cells under CSF2 and IL4/interleukin-4 treatment, and up-regulated by IFNG/IFN-gamma stimulation in monocytes. PD-L2 usually functions in a PDCD1-independent manner and is involved in regulating costimulatory signal which is essential for T-cell proliferation and IFNG production. Recent studies demonstrate that the expression of PD-L2 on the tumor cells promotes CD8 T cell–mediated rejection of tumor cells, at both the induction and effector phase of antitumor immunity. Moreover, PD-L2 binds to PD-1 cells and enhances T cell killing in a PD-1–independent mechanism.

更多有关重组小鼠PD-L2(B7-DC) 重组蛋白的价格及使用说明等，请联*(代"系")我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：
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BTN130977 生物素化的Oligo(dT) Biotinylated Oligo(dT)
WE0176 血液基因组DNA提取试剂盒  BalbGen Blood DNA Kit
SV0524 NcoI-HF限制性内切酶 NcoI-HF Restriction Endonuclease
SV1654 pCLuc Mini-TK 2 载体
BTN100203 通用型LAMP试剂盒 Universal Loop-Mediated Isothermal Amplification Kit
YT187 EMSA上样缓冲液(Gel-Shift上样缓冲液)(无色，10X) EMSA/Gel-Shift Loading Buffer
SV1368 RNase H
HR0376 丙*(代"烯")酰胺溶液(30%, 29:1) Acrylamide solution (30%, 29:1)
BTN121205 CCK-8细胞增殖及毒性检测试剂盒 Cell Counting Kit-8
YT598 腈水合酶 Nitrile Hydratase (Crude Enzyme)
SY0464 多聚D-赖*酸溶液(5mg/ml)(分子量15万～30万)(细胞培养级) Poly-D-lysine Solution (5 mg/ml), Mw 150,000-300,000
KFS224 Caspase-10蛋白检测试剂盒 Caspase-10 Detection Assay(Western Blot)
RFT161 BSA溶液(PCR级) BSA Solution(PCR Grade)
SY0251 DNA上样缓冲液 6×DNA Loading Buffer
重组小鼠PD-L2(B7-DC) 重组蛋白关键词：重组小鼠PD-L2蛋白,JN1896,重组PD-L2,重组小鼠B7-DC

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SV1531 α1-2 岩藻糖苷酶
HR0597 高尔基体染色试剂盒 Golgi staining kit
BTN130984 DNase I溶液 DNase I Solution
SY0004 蜗牛酶 Snailase
HR0191 线粒体蛋白提取试剂盒(2D电泳用) Mitochondrial protein extraction kit (2D electrophoresis)
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SY0355 4×Tris-HCl分离胶缓冲液，pH8.8 4×Tris-HCl Separating Gel Buffer, pH8.8
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YT045 细胞与组织裂解液(一氧化*(代"氮")检测用) Cell and Tissue Lysis Buffer for Nitric Oxide Assay
重组小鼠PD-L2(B7-DC) 重组蛋白关键词：重组小鼠PD-L2蛋白,JN1896,重组PD-L2,重组小鼠B7-DC


·重组人胞质苹果酸脱*酶(MDH1)
编号：JN0677
英文名称：Recombinant Human Malate Dehydrogenase, Cytoplasmic
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ser2-Ala334在C端含有His标签。

MDH1质量控制：＞95%(还原性SDS-PAGE)


MDH1制剂：液体

MDH1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于MDH1：
Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of Malate into Oxaloacetate (using NAD+) and vice versa. MDH1 should not be confused with Malic Enzyme, which catalyzes the conversion of Malate to Pyruvate, producing NADPH. MDH1 also participates in Gluconeogenesis, the synthesis of Glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by Pyruvate Carboxylase to form Pxaloacetate, a Citric Acid Cycle intermediate. In order to transport the Oxaloacetate out of the Mitochondria, Malate Dehydrogenase reduces it to Malate, and it then traverses the inner Mitochondrial membrane. Once in the cytosol, the Malate is oxidized back to Oxaloacetate by MDH1. Finally, Phosphoenol-Pyruvate Carboxy Kinase (PEPCK) converts Oxaloacetate to Phosphoenol Pyruvate.

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