规格: | 1mg | 产品价格: | 997.5 |
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规格: | 5mg | 产品价格: | 3990 |
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规格: | 10mg | 产品价格: | 6289.5 |
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Catalog Number 9001935
Synonyms R-(−)-7-Desmethyl-8-nitro Blebbistatin
Molecular Formula C17H13N3O4
Relative Molecular Mass 323.3
CAS Registry Number 1217619-62-9
Formulation A crystalline solid
λmax 234, 270, 315, 350, 443 nm
Purity ≥98%
Storage -20°C
SMILES O=C1[C@]2(O)C(N(C3=CC=CC=C3)CC2)=NC4=C1C=CC([N+]([O-])=O)=C4
产品描述
(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin (Item No. 13165), which is the inactive form of (-)-blebbistatin (Item No. 13013). Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereochemistry as the inactive (+)-blebbistatin enantiomer.
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Cayman公司成立于1980年,在过去20多年的发展过程中,始终保持着为科研工作者提供高质、优价研究产品的宗旨。该公司目前可以提供13,138 多种生化和免疫试剂,涉及肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等研究领域。非常有特色的检测试剂盒包括类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等。
温馨提示:不可用于临床ZL。