Thrombin Receptor Agonist Peptide (trifluoroacetate salt)_详细资料

产品信息

供应商：上海兰浚生物科技有限公司数量：大量英文名： Thrombin Receptor Agonist Peptide (trifluoroacetate salt) 保质期： ≥ 2 years 保存条件： -20°C 规格： 1mg

规格： 1mg 产品价格： 1837.5
Catalog Number 24710
Synonyms TRAP-14
Molecular Formula C81H118N20O23 • XCF3COOH
Relative Molecular Mass 1739.9
Formulation A lyophilized powder
Purity ≥95%
Storage -20°C
SMILES [H]N[C@@H](CO)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N1CCC[C@H]1C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N2CCC[C@H]2C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O.FC(F)(C(O)=O)F
产品描述
Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. It induces aggregation of washed platelets as well as platelets in citrated and hirudin plasma. TRAP-14 (100 μM) increases the cytosolic calcium concentration in isolated guinea pig pulmonary smooth muscle cells 5-fold over baseline. It increases pulmonary arterial pressure in isolated guinea pig lung when used at a concentration of 1 μM, which is comparable to the effect induced by 10 nM α-thrombin. TRAP-14 also induces contraction of isolated rat aortic rings and increases endothelin-1 (ET-1) levels in a dose-dependent manner, an effect that is reversed by the ETA antagonist BQ-123 and the nitric oxide synthase (NOS) inhibitor L-NNA (Item No. 80220).
更多产品信息，请点击：https://www.caymanchem.com/product/24710
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Cayman公司成立于1980年，在过去20多年的发展过程中，始终保持着为科研工作者提供高质、优价研究产品的宗旨。该公司目前可以提供13,138 多种生化和免疫试剂，涉及肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等研究领域。非常有特色的检测试剂盒包括类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等。

温馨提示：不可用于临床ZL。

规格：	1mg	产品价格：	1837.5

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