重组小鼠ACVRL1(ALK-1)(激活素受体样激酶1) 重组蛋白

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北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组小鼠ACVRL1(ALK-1)(激活素受体样激酶1) 重组蛋白在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组小鼠ACVRL1(ALK-1)(激活素受体样激酶1) 重组蛋白
产地：国产|进口
英文名：Recombinant Mouse Activin Receptor-like Kinase 1
编号：JN1431
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp23-Pro119在C端带有Fc标签。

ACVRL1/ALK-1 质量控制：＞95%(还原性SDS-PAGE)

ACVRL1/ALK-1 制剂：冻干品

ACVRL1/ALK-1 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ACVRL1/ALK-1 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ACVRL1/ALK-1 ：
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angiogenesis during embryogenesis, wound healing, and tumor growth. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. ALK-1 is mainly expressed in endothelial cells regulating proliferation and migration in vitro and angiogenesis in vivo. Mutations in ALK-1 as well as in endoglin are associated with hereditary hemorrhagic telangiectasia (HHT), suggesting ALK-1 plays a critical role for in the control of blood vessel development or repair.

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重组小鼠ACVRL1(ALK-1)(激活素受体样激酶1) 重组蛋白关键词：重组小鼠ALK-1,重组小鼠激活素受体样激酶1,重组小鼠ACVRL1,JN1431,重组小鼠ACVRL1蛋白

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重组小鼠ACVRL1(ALK-1)(激活素受体样激酶1) 重组蛋白关键词：重组小鼠ALK-1,重组小鼠激活素受体样激酶1,重组小鼠ACVRL1,JN1431,重组小鼠ACVRL1蛋白


·重组人MASP1(甘露聚糖结合凝集素丝*酸蛋白酶1)
编号：JN1733
英文名称：Recombinant Human Mannan-Binding Lectin Serine Protease 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的His20-Arg728在C端含有His标签。

MASP1质量控制：＞95%(还原性SDS-PAGE)

MASP1制剂：液体

MASP1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于MASP1：
Mannan-Binding Lectin Serine Protease 1 (MASP-1) belongs to the peptidase S1 family. MASP1 contains two CUB domains, one EGF-like domain, one peptidase S1 domain and two Sushi (CCP/SCR) domains. MASP1 is primarily expressed in liver. MASP1 involved in the lectin pathway of the complement, performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. MASP1 is synthesized as a zymogen and activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. MASP1 is not directly involved in complement activation but may act as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP2. MASP1 is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. MASP1 is inhibited by SERPING1 and A2M.

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