KRT19 / CK19 / Cytokeratin 19 Antibody (Internal) | LBP83759 | Leading Biology

商品分类：多克隆抗体

产品概述：Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

靶点/蛋白：Synthetic peptide corresponding to an internal sequence surrounding amino acid 120 of human keratin-19

来源：Rabbit

参考文献：Stasiak P.C.,et al.Nucleic Acids Res. 15:10058-10058(1987).Bader B.L.,et al.Eur. J. Cell Biol. 47:300-319(1988).Eckert R.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1114-1118(1988).Stasiak P.C.,et al.J. Invest. Dermatol. 92:707-716(1989).Whittock N.V.,et al.Biochem. Biophys. Res. Commun. 267:462-465(2000).

特异性：Human, Mouse, Monkey, Dog

别名：Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19

应用：IHC-P (5 μg/ml)

简单描述：Rabbit Polyclonal KRT19 / CK19 / Cytokeratin 19 Antibody (Internal). Validated for use in WB, IHC-P.

详情：FunctionInvolved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.Tissue_LocationExpressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.

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