DRD3 / Dopamine Receptor D3 Antibody (Cytoplasmic Domain) | LBP77941 | Leading Biology

商品分类：多克隆抗体

产品概述：Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.

靶点/蛋白：Human DRD3 / Dopamine Receptor D3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

来源：Rabbit

参考文献：Giros B.,et al.C. R. Acad. Sci. III, Sci. Vie 311:501-508(1990).Schmauss C.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:8942-8946(1993).Liu K.,et al.J. Biol. Chem. 269:29220-29226(1994).Fishburn C.S.,et al.Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.Muzny D.M.,et al.Nature 440:1194-1198(2006).

特异性：Human, Mouse, Hamster, Monkey, Pig, Horse, Dog

别名：D(3) dopamine receptor, Dopamine D3 receptor, DRD3

应用：IHC-P (16-32 μg/ml)

简单描述：Rabbit Polyclonal DRD3 / Dopamine Receptor D3 Antibody (Cytoplasmic Domain). Validated for use in IHC-P.

详情：FunctionDopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.Cellular_LocationCell membrane; Multi-pass membrane protein Note=Both membrane-bound and scattered in the cytoplasm during basal conditions. Receptor stimulation results in the rapid internalization and sequestration of the receptors at the perinuclear area (5 and 15 minutes), followed by the dispersal of the receptors to the membrane (30 minutes). DRD3 and GRK4 co- localize in lipid rafts of renal proximal tubule cellsTissue_LocationBrain.

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