Anti-Rat GABA Transporter 3 (C-Terminal) Antibody | LBP77329 | Leading Biology

商品分类：多克隆抗体

靶点/蛋白：ABD10983 recognises an epitope within the C-terminal region (CT) of rat GABA transporter 3, otherwise known as GAT-3, a 67kDa high-affinity Na+/Cl- dependent plasma membrane transporter and member of the sodium: neurotransmitter symporter (SNF) family, expressed in the cerebral cortex and retina.GAT-3 is one of a group of proteins involved in the regulation of GABAergic synaptic neurotransmission, through the uptake and release of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter of the mammalian central nervous system, which must be maintained at the correct level to ensure successful synaptic transmission. Further GABA transporter genes identified are GAT-1, GAT-2 and GAT-4, and many studies have linked neurotransmitter transporters with neurological disorders, including epilepsy and ischemia.

来源：Rabbit

参考文献：1. Conti, F. et al. (2004) GABA transporters in the mammalian cerebral cortex: localization, development and pathological implications.Brain Res. Rev. 45: 196-212.2. Allen, N.J. et al. (2004) Reversal or reduction of glutamate and GABA transport in CNS pathology and therapy.Eur. J. Physiol. 449: 132-142.

特异性：Rat

别名：Sodium- and chloride-dependent GABA transporter 3, GAT-3, Solute carrier family 6 member 11, Slc6a11, Gabt3, Gat-3, Gat-b

简单描述：Rabbit Polyclonal Anti-Rat GABA Transporter 3 (C-Terminal) Antibody . Validated for use in WB.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层