Alpha-1-Antichymotrypsin Antibody (aa222-236) | LBP77166 | Leading Biology

商品分类：多克隆抗体

产品概述：Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

靶点/蛋白：Human SERPINA3.

来源：Goat

参考文献：Chandra T.,et al.Biochemistry 22:5055-5061(1983).Poller W.,et al.Genomics 17:740-743(1993).Kim J.W.,et al.Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004).Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.

特异性：Human

别名：Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, SERPINA3, AACT

应用：ELISA (1:128000), IHC-P (5 μg/ml), WB (0.3-1 μg/ml)

简单描述：Goat Polyclonal Alpha-1-Antichymotrypsin Antibody (aa222-236). Validated for use in WB, IHC-P, E.

详情：FunctionAlthough its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.Cellular_LocationSecreted.Tissue_LocationPlasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains

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