SORBS1/ponsin (internal region) Antibody (internal region) | LBP85146 | Leading Biology

商品分类：多克隆抗体

产品概述：This antibody is expected to recognise all reported isoforms (NP_006425.2 and NP_056200.1 and NP_001030126.1 and NP_001030127.1 and NP_001030128.1 and NP_079267.1 and NP_001030129.1)

来源：Goat

存储溶液：0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

参考文献：CAP defines a second signalling pathway required for insulin-stimulated glucose transport. Baumann CA, Ribon V, Kanzaki M, Thurmond DC, Mora S, Shigematsu S, Bickel PE, Pessin JE, Saltiel AR. Nature. 2000 Sep 14;407(6801):202-7. PMID: 11001060

特异性：' + item.reactivity + '

别名：Sorbin and SH3 domain-containing protein 1, Ponsin, SH3 domain protein 5, SH3P12, c-Cbl-associated protein, CAP, SORBS1 (HGNC:14565)

简单描述：Goat Polyclonal SORBS1/ponsin (internal region) Antibody (internal region). Validated for use in E.

详情：FunctionPlays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin- stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).Cellular_LocationCell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion Nucleus. Nucleus matrix Note=Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.Tissue_LocationDetected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.

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企业 QQ：3212874516、3198592576

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