商品分类:多克隆抗体
产品概述:High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
靶点/蛋白:Human MTNR1A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
来源:Rabbit
参考文献:Reppert S.M.,et al.Neuron 13:1177-1185(1994).Ebisawa T.,et al.Biochem. Biophys. Res. Commun. 262:832-837(1999).Huang Y.-H.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
特异性:Human
别名:Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor, MTNR1A
应用:IHC-P (5-10 μg/ml)
简单描述:Rabbit Polyclonal MTNR1A / Melatonin Receptor 1a Antibody (Cytoplasmic Domain). Validated for use in IHC-P.
详情:FunctionHigh affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.Cellular_LocationCell membrane; Multi-pass membrane protein.Tissue_LocationExpressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus
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