PPARD / PPAR Delta Antibody (Internal) | LBP74971 | Leading Biology

商品分类：多克隆抗体

产品概述：Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.

靶点/蛋白：PPAR delta

来源：Rabbit

参考文献：Schmidt A.,et al.Mol. Endocrinol. 6:1634-1641(1992).Skogsberg J.,et al.Int. J. Mol. Med. 6:73-81(2000).Kobayashi T.,et al.FEBS Lett. 582:2737-2744(2008).Cho M.-C.,et al.Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004).

特异性：Human, Mouse, Rat

别名：Peroxisome proliferator-activated receptor delta, PPAR-delta, NUCI, Nuclear hormone receptor 1, NUC1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, PPAR-beta, PPARD, NR1C2, PPARB

应用：ELISA (1:2000-1:8000), IHC-P (2.5 μg/ml), WB (1:500-1:2000)

简单描述：Rabbit Polyclonal PPARD / PPAR Delta Antibody (Internal). Validated for use in WB, IHC-P, E.

详情：FunctionLigand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.Cellular_LocationNucleus.Tissue_LocationUbiquitous with maximal levels in placenta and skeletal muscle

生物商城：http://www.annoron.com

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企业 QQ：3212874516、3198592576

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