Phospholamban / PLN Antibody (N-Term) | LBP74838 | Leading Biology

商品分类：多克隆抗体

来源：Goat

存储溶液：0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

参考文献：The role of Lamin A/C mutations in Danish patients with idiopathic dilated cardiomyopathy. M?ller DV, Pham TT, Gustafsson F, Hedley P, Ersb?ll MK, Bundgaard H, Andersen CB, Torp-Pedersen C, K?ber L, Christiansen M. European journal of heart failure : journal of the Working Group on Heart Failure of the European Society of Cardiology 2009 Nov 11 (11): 1031-5. PMID: 19875404

特异性：Human, Rat

别名：Cardiac phospholamban, PLB, PLN, PLB

简单描述：Goat Polyclonal Phospholamban / PLN Antibody (N-Term). Validated for use in WB, E.

详情：FunctionReversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.Cellular_LocationSarcoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane proteinTissue_LocationHeart muscle (at protein level).

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企业 QQ：3212874516、3198592576

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