TREM2 / TREM-2 Antibody (C-Terminus) | LBP70810 | Leading Biology

商品分类：多克隆抗体

产品概述：May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.

靶点/蛋白：Human TREM2.

来源：Goat

参考文献：Bouchon A.,et al.J. Immunol. 164:4991-4995(2000).Begum N.A.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.Paloneva J.,et al.Am. J. Hum. Genet. 71:656-662(2002).Paloneva J.,et al.Am. J. Hum. Genet. 72:225-225(2003).

特异性：Human

别名：Triggering receptor expressed on myeloid cells 2, TREM-2, Triggering receptor expressed on monocytes 2, TREM2

应用：ELISA (1:32000), IHC-P (2.5 μg/ml),

简单描述：Goat Polyclonal TREM2 / TREM-2 Antibody (C-Terminus). Validated for use in IHC-P, E.

详情：FunctionMay have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.Cellular_LocationIsoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted.Tissue_LocationExpressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord.

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企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层