商品分类:多克隆抗体
产品概述:Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neioring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
来源:Rabbit
参考文献:Fishman G.I.,et al.J. Cell Biol. 111:589-598(1990).Fishman G.I.,et al.Genomics 10:250-256(1991).Haefliger J.-A.,et al.Eur. Heart J. 20:1843-1843(1999).Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004).
特异性:Human, Mouse, Rat
别名:Gap junction alpha-1 protein, Connexin-43, Cx43, Gap junction 43 kDa heart protein, GJA1, GJAL
应用:IHC-P (1:25), WB (2-4 μg/ml),
简单描述:Rabbit Polyclonal GJA1 / CX43 / Connexin 43 Antibody (3rd Cytoplasmic Domain). Validated for use in WB, IHC-P.
详情:FunctionGap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neioring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).Cellular_LocationCell membrane; Multi-pass membrane protein. Cell junction, gap junctionTissue_LocationExpressed in the heart and fetal cochlea.
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