Anti-Human Fractalkine Antibody (Biotin) | LBP64470 | Leading Biology

商品分类：多克隆抗体

靶点/蛋白：Rabbit anti-Human Fractalkine antibody recognizes human fractalkine, otherwise known as CX3CL1, a 397 amino acid CX3C chemokine which signals through the CX3CR1 receptor and is expressed by various tissues including the brain, testis, lung, heart, kidney, colon and skeletal muscle.Adhesion of fractalkine to the CX3CR1 receptor triggers the chemotaxis and adhesion of leucocytes, including T cells, monocytes and NK cells and studies have suggested that fractalkine is involved in the regulation of brain microglia during neuroinflammatory processes (Sunnemarket al.2005). CX3CL1 may also play a role in dendritic cellmediated host defense against invading pathogens such as Legionella pneumophila(Kikuchiet al.2005).

来源：Rabbit

参考文献：1. Sunnemark, D. et al. (2005) CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental immune encephalomyelitis: kinetics and cellular origin. J. Neuroinflamm. 2: 17.2. Kikuchi, T. et al. (2005) Involvement of Fractalkine/CX3CL1 expression by dendritic cells in the enhancement of host immunity against Legionella pneumophila.Infect. Immun. 73: 5350-5357.

特异性：Human

别名：Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, Processed fractalkine, CX3CL1, FKN, NTT, SCYD1

简单描述：Rabbit Polyclonal Anti-Human Fractalkine Antibody (Biotin). Validated for use in WB, E.

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