ACE2 / ACE-2 Antibody (Internal) | LBP64369 | Leading Biology

商品分类：多克隆抗体

产品概述：Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

靶点/蛋白：synthetic peptide corresponding to amino acids near the center of human ACE2

来源：Rabbit

参考文献：Donoghue M.,et al.Circ. Res. 87:E1-E9(2000).Tipnis S.R.,et al.J. Biol. Chem. 275:33238-33243(2000).Douglas G.C.,et al.Endocrinology 145:4703-4711(2004).Itoyama S.,et al.Am. J. Med. Genet. A 136:52-57(2005).Suzuki Y.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.

特异性：Human

别名：Angiotensin-converting enzyme 2, 3.4.17.23, ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog, ACEH, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2, ACE2

应用：IHC-P (2.5 μg/ml), WB (0.5-2 μg/ml),

简单描述：Rabbit Polyclonal ACE2 / ACE-2 Antibody (Internal). Validated for use in WB, IHC-P, IF, E.

详情：FunctionCarboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.Cellular_LocationProcessed angiotensin-converting enzyme 2: SecretedTissue_LocationExpressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level) Expressed in heart, kidney, testis, and gastrointestinal system

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地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层