商品分类:多克隆抗体
产品概述:Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
靶点/蛋白:TOP2A Antibody detects endogenous levels of total TOP2A protein.
来源:Rabbit
参考文献:Tsai-Pflugfelder M.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:7177-7181(1988).Wasserman R.A.,et al.Cancer Res. 53:3591-3596(1993).Lang A.J.,et al.Gene 221:255-266(1998).Sng J.H.,et al.Biochim. Biophys. Acta 1444:395-406(1999).Zody M.C.,et al.Nature 440:1045-1049(2006).
特异性:Human
别名:DNA topoisomerase 2-alpha, 5.99.1.3, DNA topoisomerase II, alpha isozyme, TOP2A, TOP2
应用:ELISA (1:20000), IF (1:100-1:500), IHC-P (10 μg/ml), WB (1:500-1:1000) ,
简单描述:Rabbit Polyclonal TOP2A / Topoisomerase II Alpha Antibody (aa1-50). Validated for use in WB, IHC-P, IF, E.
详情:FunctionControl of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).Cellular_LocationCytoplasm. Nucleus, nucleoplasm. Note=Generally located in the nucleoplasm
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企业 QQ:3212874516、3198592576
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温馨提示:不可用于临床ZL。