PLG / Plasmin / Plasminogen Antibody | LBP63015 | Leading Biology

商品分类：多克隆抗体

产品概述：Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.

靶点/蛋白：Mouse PLG / Plasmin / Plasminogen

来源：Sheep

参考文献：Petersen T.E.,et al.J. Biol. Chem. 265:6104-6111(1990).Forsgren M.,et al.FEBS Lett. 213:254-260(1987).Browne M.J.,et al.Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases.Mungall A.J.,et al.Nature 425:805-811(2003).Sottrup-Jensen L.,et al.Submitted (JUL-1977) to the PIR data bank.

特异性：Human, Mouse, Rat

别名：PLG, Plasmin, Plasminogen

应用：ELISA (10 μg/ml), IHC-P (5 μg/ml), WB (10 μg/ml),

简单描述：Sheep Polyclonal PLG / Plasmin / Plasminogen Antibody. Validated for use in WB, IHC-P, E.

详情：FunctionPlasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.Cellular_LocationSecreted. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin Interaction with HRG tethers it to the cell surfaceTissue_LocationPresent in plasma and many other extracellular fluids. It is synthesized in the liver

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