IQSEC1 Antibody (N-Terminus) | LBP61954 | Leading Biology

商品分类：多克隆抗体

产品概述：In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.

靶点/蛋白：IQSEC1 antibody is human, mouse and rat reactive. At least four isoforms of IQSEC1 are known to exist. IQSEC1 antibody is predicted to not cross-react with IQSEC2.

来源：Rabbit

参考文献：Dunphy J.L.,et al.Curr. Biol. 16:315-320(2006).Nagase T.,et al.DNA Res. 5:277-286(1998).Someya A.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:2413-2418(2001).Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).

特异性：Human, Mouse, Rat

别名：IQSEC1, ARF-GEP100, ARFGEP100, Brefeldin A-resistant ARF-GEF2, BRAG2, IQ motif and Sec7 domain 1, KIAA0763, GEP100

应用：IHC-P (10 μg/ml), WB (1 - 2 μg/ml),

简单描述：Rabbit Polyclonal IQSEC1 Antibody (N-Terminus). Validated for use in WB, IHC-P, E.

详情：FunctionIn addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.Cellular_LocationCytoplasm. Nucleus. Note=At steady state, may be preferentially cytosolicTissue_LocationExpressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis.

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企业 QQ：3212874516、3198592576

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