Prolactin Receptor (hPRL-Receptor) Antibody | LM15996 | Leading Biology

商品分类：单克隆抗体

产品概述：It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

来源：Mouse

参考文献：Br J Cancer. 2011;104(10):1641-8. | Breast Cancer Res. 2008;10(4):R68

特异性：Human

别名：Prolactin receptor, PRL-R, PRLR

简单描述：Mouse Monoclonal Prolactin Receptor (hPRL-Receptor) Antibody. Validated for use in IHC, IF, FC. Clone: PRLR742.

详情：FunctionThis is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.Cellular_LocationMembrane; Single-pass type I membrane proteinTissue_LocationExpressed in breast, placenta, kidney, liver and pancreas.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层