NME2 Antibody (monoclonal) (M08) | LM15699 | Leading Biology

商品分类：单克隆抗体

产品概述：Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neioring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) which encode a fusion protein comprised of sequence sharing identity with each individual gene product.

靶点/蛋白：NME2 (NP_002503, 51 a.a. ~ 152 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

来源：mouse

存储溶液：Clear, colorless solution in phosphate buffered saline, pH 7.2.

参考文献：Nme protein family evolutionary history, a vertebrate perspective. Desvignes T, et al. BMC Evol Biol, 2009 Oct 23. PMID 19852809.Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import. Munkonge FM, et al. J Biol Chem, 2009 Sep 25. PMID 19638341.Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis. Treharne KJ, et al. FEBS Lett, 2009 Sep 3. PMID 19619546.Role of nm23 in the regulation of cell shape and migration via Rho family GTPase signals. Miyamoto M, et al. Mol Cell Biochem, 2009 Sep. PMID 19381785.NM23H2 inhibits EGF- and Ras-induced proliferation of NIH3T3 cells by blocking the ERK pathway. Lee MY, et al. Cancer Lett, 2009 Mar 18. PMID 19022560.

特异性：Human, Mouse, Rat

别名：Nucleoside diphosphate kinase B, NDK B, NDP kinase B, C-myc purine-binding transcription factor PUF, Histidine protein kinase NDKB, nm23-H2, NME2, NM23B

应用：WB~~1:500~1000

简单描述：mouse Monoclonal NME2 Antibody (monoclonal) (M08). Validated for use in WB, IF. Clone: 1F2.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层