商品分类:单克隆抗体
产品概述:The protein encoded by this gene is the human homolog of the mouse VpreB3 (8HS20) protein, and is specifically expressed in cell lines representative of all stages of B-cell differentiation. It is also related to VPREB1 and other members of the immunoglobulin supergene family. This protein associates with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. The precise function of the protein is not known, but it may contribute to mu chain transport in pre-B cells.
靶点/蛋白:VPREB3 (NP_037510, 24 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
来源:mouse
存储溶液:Clear, colorless solution in phosphate buffered saline, pH 7.2.
参考文献:Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.Assembly of the kappa preB receptor requires a V kappa-like protein encoded by a germline transcript. Rangel R, et al. J Biol Chem, 2005 May 6. PMID 15757909.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.A genome annotation-driven approach to cloning the human ORFeome. Collins JE, et al. Genome Biol, 2004. PMID 15461802.Binding of free immunoglobulin light chains to VpreB3 inhibits their maturation and secretion in chicken B cells. Rosnet O, et al. J Biol Chem, 2004 Mar 12. PMID 14670953.
特异性:Human
别名:Pre-B lymphocyte protein 3, N27C7-2, Protein VPreB3, VPREB3
应用:WB~~1:500~1000
简单描述:mouse Monoclonal VPREB3 Antibody (monoclonal) (M08). Validated for use in WB. Clone: 4H8.
生物商城:http://www.annoron.com
办公电话:010-56256916
官方售后:400-965-8633
企业 QQ:3212874516、3198592576
地 址:北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示:不可用于临床ZL。