Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody | LM19747 | Leading Biology

商品分类：单克隆抗体

产品概述：This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations.

来源：Mouse

参考文献：Moinfar F et. al. Am J Surg Pathol 1999;23(9):1048-58,2. Varma M et. al. Mod Pathol 1999;12(5):472-

特异性：Human, Mouse, Rat

别名：Keratin, type II cytoskeletal 1, 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1, KRT1, KRTA

简单描述：Mouse Monoclonal Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody. Validated for use in WB, IHC, IF, FC. Clone: SPM591.

详情：FunctionMay regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.Cellular_LocationCell membrane. Note=Located on plasma membrane of neuroblastoma NMB7 cellsTissue_LocationThe source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层