Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Antibody - Without BSA and Azide | LM19616 | Leading Biology

商品分类：单克隆抗体

产品概述：This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

来源：Mouse

存储溶液：200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

参考文献：Barrott JJ et al. Proc Natl Acad Sci U S A 108:12752-7 (2011) | Reichelt J et al. J Cell Sci 110 ( Pt 18):2175-86 (1997

特异性：Human, Mouse

别名：Keratin, type I cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, K10, KRT10, KPP

简单描述：Mouse Monoclonal Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Antibody - Without BSA and Azide. Validated for use in IHC-P, IF, FC. Clone: SPM261.

详情：Tissue_LocationSeen in all suprabasal cell layers including stratum corneum

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层