Glycogen-Synthase Antibody (C-term) | LM17043 | Leading Biology

商品分类：单克隆抗体

产品概述：Glycogen synthase is an enzyme of the transferase class that catalyses the reaction of UDP-glucose and (1,4-α-D-glucosyl)n to yield UDP and (1,4-α-D-glucosyl)n+1 (1-2). This tetrameric enzyme is the rate-limiting step for glycogen synthesis (3). Glycogen concentrations are regulated by the complementary activities of glycogen phosphorylase and glycogen synthase. Glycogen synthase activity is regulated by phosphorylation of serine residues and by insulin stimulation (4). Glycogen synthase is known to have two forms; the unphosphorylated and most active form, synthase-a, and the phosphorylated glucose-6-phosphate-dependent form, synthase-b.

靶点/蛋白：A synthetic peptide corresponding to residues in the C-terminus of the human glycogen synthase was used as immunogen.

来源：Rabbit

存储溶液：50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

参考文献：1. Browner, M. F.; Nakano, K.; Bang, A. G.; Fletterick, R. J. : Proc. Nat. Acad. Sci. 86: 1443-1447, 1989.
2. Skurat, A., and Roach, P. J. (1996) in Diabetes Mellitus pp. 213-222.
3. Hardy, T. A., and Roach, P. J. (1993) J. Biol. Chem. 268, 23799-23805
4. Skurat, A. V., Wang, Y. & Roach, P. J. (1994) J. Biol. Chem. 269, 25534


特异性：Human, Mouse, Rat

别名：Glycogen [starch] synthase, muscle, GYS1, GYS

应用：WB~~1:500

简单描述：Rabbit Monoclonal Glycogen-Synthase Antibody (C-term). Validated for use in WB, IF. Clone: EP817Y.

详情：FunctionTransfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层