Cytochrome-C Antibody (oxidase subunit 2) | LM16802 | Leading Biology

商品分类：单克隆抗体

产品概述：Cytochrome c oxidase subunit 2 (CO2 or MTCO2) is 1 of 3 mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. It collects electrons from ferrocytochrome c (reduced cytochrome c) and transfers them to oxygen to give water. The energy released is used to transport protons across the mitochondrial inner membrane. Complex IV is composed of 13 polypeptides. Subunits 1, 2 and 3 are encoded by the mtDNA while the remaining subunits are nuclear encoded (1-3).

靶点/蛋白：A synthetic peptide corresponding to residues in human Cytochrome C Oxidase subunit 2 was used as an immunogen.

来源：Rabbit

存储溶液：50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

参考文献：1. Kadenbach B, et al. Anal Biochem. 129(2):517-21, 1983
2. Capaldi RA., et al. Annu Rev Biochem.59:569-96, 1990
3. Shoffner, J.M., et al. The Metabolic and Molecular Basis of Inherited Disease 1(7):1535−1609


特异性：Human

别名：Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II, MT-CO2, COII, COXII, MTCO2

应用：WB~~1:10000~50000IHC~~1:100~250

简单描述：Rabbit Monoclonal Cytochrome-C Antibody (oxidase subunit 2). Validated for use in WB, IHC, IF. Clone: EPR3314.

详情：FunctionCytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.Cellular_LocationMitochondrion inner membrane; Multi-pass membrane protein

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