商品分类:单克隆抗体
产品概述:APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes.Anti-APRIL (mouse) Monoclonal Antibody (recombinant) (Blocking) (APRY-1-1) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
靶点/蛋白:Recognizes mouse APRIL. Does not recognize mouse BAFF.
来源:Purified From?HEK 293 Cell?culture Supernatant.
存储溶液:Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
特异性:Mouse
别名:A Proliferation Inducing Ligand; TNFSF13; CD256; TALL-2
简单描述:Purified From?HEK 293 Cell?culture Supernatant. Monoclonal Functional APRIL (mouse) Antibody, mAb (recombinant) (blocking) (preservative free). Validated for use in E, IP. Clone: Apry-1-1.
详情:FunctionCytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.Cellular_LocationSecreted.
生物商城:http://www.annoron.com
办公电话:010-56256916
官方售后:400-965-8633
企业 QQ:3212874516、3198592576
地 址:北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层
温馨提示:不可用于临床ZL。