TGF-alpha (Transforming Growth Factor alpha) Antibody - With BSA and Azide | LM11080 | Leading Biology

商品分类：单克隆抗体

产品概述：This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGFα (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

靶点/蛋白：A 10-amino acid synthetic peptide (aa34-43) from human TGFα.

来源：Mouse

存储溶液：0.5 ml at 200ug/ml with BSA and azide

参考文献：1. Bebok Z; Szekeres G; Horvath G; Duda E; Nemeth P. [Creation of monoclonal antibodies against tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor alpha (TFG-alpha), their definition and possible use]. Orvosi Hetilap, 1993, 134(24):1303-7. Language: Hungarian.2. Bebok Z; Markus B; Nemeth P. Prognostic relevance of transforming growth factor alpha (TGF-alpha) and tumor necrosis factor alpha (TNF-alpha) detected in breast cancer tissues by immunohistochemistry. Breast Cancer Research and Treatment, 1994, 29(3):229-35.3. Nasim, M. M., Thomas, D. M., Alison, M. R., and Fil]ipe, M. I. Transforming growth factor a expression in normal gastric mucosa, intestinal metaplasia, dysplasia and gastric carcinoma – an immunohistochemical study, Histopathology. 20: 339-343, 1992.

特异性：Human, Zebrafish, Rabbit

别名：Protransforming growth factor alpha, Transforming growth factor alpha, TGF-alpha, EGF-like TGF, ETGF, TGF type 1, TGFA

简单描述：Mouse Monoclonal TGF-alpha (Transforming Growth Factor alpha) Antibody - With BSA and Azide. Validated for use in WB, IHC, FC, IP, E. Clone: TG86.

详情：FunctionTGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.Cellular_LocationTransforming growth factor alpha: Secreted, extracellular spaceTissue_LocationIsoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines

生物商城：http://www.annoron.com

办公电话：010-56256916

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企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层