Human Apolipoprotein-H (B2-Glycoprotein-1) | HAPO-H | Enzyme Research Laboratories

商品分类：重组蛋白

研究领域：Platelet & Plasma Proteins

产品概述：B2Glycoprotein-1 (B2GP-1), also known as Apolipoprotein-H is a plasma glycoprotein that circulates at a concentration of 200 ug/ml (4 uM). B2GP-1 has been identified as a constituent of chylomicrons, very low density lipoproteins and high density lipoproteins in human plasma. It has also been demonstrated to bind phospholipids, heparin and platelets where it can modulate the activity of adenylate (19%). Although the precise function(s) are as yet unknown, B2GP-1 has been shown to interfere with blood coagulation by competitively binding to phospholipids exposed during cell activation or damage. Recent evidence also implicates B2GP-1 as a cofactor recognized by some anti-phospholipid antibodies present in autoimmune disorders such as systemic lupus erythematosus (SLE).

存储溶液：Buffer Composition = 20 mM Tris-HCl / 0.3 M NaCl / pH 7.3Extinction Coefficient (1%) = 9.4Molecular Weight = 48,000 daltons

简单描述：HAPO-H, B2Glycoprotein-1 (B2GP-1), also known as Apolipoprotein-H is a plasma glycoprotein that circulates at a concentration of 200 ug/ml (4 uM). B2GP-1 has been identified as a constituent of chylomicrons, very low density lipoproteins and high density lipoproteins in human plasma. It has also been demonstrated to bind phospholipids, heparin and platelets where it can modulate the activity of adenylate (19%). Although the precise function(s) are as yet unknown, B2GP-1 has been shown to interfere with blood coagulation by competitively binding to phospholipids exposed during cell activation or damage. Recent evidence also implicates B2GP-1 as a cofactor recognized by some anti-phospholipid antibodies present in autoimmune disorders such as systemic lupus erythematosus (SLE).

详情：Related ProductsApolipoprotein-H (B2-Glycoprotein-1) ELISA Goat Anti-Human B2-Glycoprotein-1 (Apolipoprotein-H) Affinity Purified IgG Goat Anti-Human B2-Glycoprotein-1 (Apolipoprotein-H) Peroxidase Conjugated IgG Goat Anti-Human B2-Glycoprotein-1 (Apolipoprotein-H) Purified IgG Apolipoprotein-H Deficient Plasma

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