特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人Ephrin-A1(肝配蛋白A1)(蝶素A1) 分子生物学试剂,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人Ephrin-A1(肝配蛋白A1)(蝶素A1) 分子生物学试剂
规格:10μg|50μg|500μg|1mg
编号:JN0831
品Pai:百奥莱博
英文名:Recombinant Human Ephrin-A1
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Asp19-Ser182在C端含有His标签。
Ephrin-A1质量控制:>95%(还原性SDS-PAGE)
Ephrin-A1制剂:冻干品
Ephrin-A1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Ephrin-A1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Ephrin-A1:
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues comp*(代"a")red to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.
更多有关重组人Ephrin-A1(肝配蛋白A1)(蝶素A1) 分子生物学试剂的价格及使用说明等,请联系我们的业务经理王欣女士咨询,我公司还销*(代"售")以下产品:
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重组人Ephrin-A1(肝配蛋白A1)(蝶素A1) 分子生物学试剂关键词:JN0831,重组人Ephrin-A1蛋白,重组人蝶素A1,重组人肝配蛋白A1
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重组人Ephrin-A1(肝配蛋白A1)(蝶素A1) 分子生物学试剂关键词:JN0831,重组人Ephrin-A1蛋白,重组人蝶素A1,重组人肝配蛋白A1
·重组人BH3结构域凋亡诱导蛋白(BID)
编号:JN1912
英文名称:Recombinant Human BH3-Interacting Domain Death Agonist
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Asp195表达纯化得来。
BID/BH3-interacting domain death agonist质量控制:>95%(还原性SDS-PAGE)
BID/BH3-interacting domain death agonist制剂:液体
BID/BH3-interacting domain death agonist保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于BID/BH3-interacting domain death agonist:
BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint.
我公司正在火爆促销分子生物学试剂系列产品,欢迎您的垂询选购重组人Ephrin-A1(肝配蛋白A1)(蝶素A1) 分子生物学试剂。
温馨提示:不可用于临床ZL。