特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
北京百奥莱博专业生产供应重组小鼠VISTA(B7-H5) 分子生物学试剂,我公司销*(代"售")全品类的分子生物学试剂,价格优惠,欢迎广大科研工作者垂询订购。
名称:重组小鼠VISTA(B7-H5) 分子生物学试剂
编号:JN1617
英文名:Recombinant Mouse Platelet receptor Gi24
品Pai:百奥莱博
规格:10μg|50μg|500μg|1mg
产地:国产|进口
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe33-Ala191在C端含有His标签。
VISTA/B7-H5质量控制:>95%(还原性SDS-PAGE)
VISTA/B7-H5制剂:冻干品
VISTA/B7-H5保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
VISTA/B7-H5复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于VISTA/B7-H5:
Mouse Platelet receptor Gi24(VISTA) is a transmembrane glycoprotein with homology to B7like immune costimulatory molecules. Mature mouse Gi24 contains a 159 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane segment, and a 97 aa cytoplasmic domain. VISTA promotes both MT1-MMP expression and the MT1-MMP mediated activation of MMP-2. It supports the differentiation of embryonic stem cells (ESC) and enhances BMP-4 induced signaling in ESC, but it is also down-regulated following BMP-4 exposure. It binds to BMP-4 directly and also associates with the type I BMP receptor Activin RIB/ALK-4. It is expressed on the surface of naïve CD4+ T cells and regulatory T cells. It is up-regulated in vivo on activated monocytes and dendritic cells. VISTA inhibits CD4+ and CD8+ T cell proliferation and their production of IL-2 and IFN-γ. Its expression on tumor cells attenuates the antitumor immune response and enables more rapid tumor progression.
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我公司的重组小鼠VISTA(B7-H5) 分子生物学试剂,性价比高,货期短,送货上门,欢迎您来电咨询购买,另外,我公司还生产供应销*(代"售")下列产品:
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重组小鼠VISTA(B7-H5) 分子生物学试剂关键词:重组小鼠VISTA,JN1617,重组小鼠B7-H5,重组VISTA,重组小鼠VISTA蛋白
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·重组小鼠OX40(TNFRSF4)(N端Fc标签)
编号:JN0486
英文名称:Recombinant Mouse OX40L Receptor
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Val20-Pro211在N端带有Fc标签。
OX40/TNFRSF4质量控制:>95%(还原性SDS-PAGE)
OX40/TNFRSF4制剂:冻干品
OX40/TNFRSF4保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
OX40/TNFRSF4复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于OX40/TNFRSF4:
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
重组小鼠VISTA(B7-H5) 分子生物学试剂关键词:重组小鼠VISTA,JN1617,重组小鼠B7-H5,重组VISTA,重组小鼠VISTA蛋白
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我公司正在火爆促销分子生物学试剂系列产品,欢迎您的垂询选购重组小鼠VISTA(B7-H5) 分子生物学试剂。
温馨提示:不可用于临床ZL。