特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)促销在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)促销
品Pai:百奥莱博
编号:JN0841
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9
产地:国产|进口
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln31-Gln152&Ser153-Gln692在C端含有His标签。
PCSK9质量控制:>95%(还原性SDS-PAGE)
PCSK9制剂:液体
PCSK9保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PCSK9:
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.
重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)促销极具性价比,此外,我公司正火爆促销以下产品:
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重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)促销关键词:重组人PCSK9,重组人PCSK9蛋白,C端His标签,JN0841,重组人前蛋白转化酶枯草杆菌蛋白酶kexin-9
·重组人激活转录因子1(ATF1)
编号:JN0884
英文名称:Recombinant Human Activating Transcription Factor 1
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Val271在C端含有His标签。
ATF1质量控制:>95%(还原性SDS-PAGE)
ATF1制剂:冻干品
ATF1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
ATF1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于ATF1:
Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. ATF1 binds the cAMP response element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), a sequence present in many viral and cellular promoters. It also binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes, represses the expression of FTH1 and other antioxidant detoxification genes, triggers cell proliferation and transformation. ATF1 is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and CDK3. Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.
重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)促销关键词:重组人PCSK9,重组人PCSK9蛋白,C端His标签,JN0841,重组人前蛋白转化酶枯草杆菌蛋白酶kexin-9
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我公司正在打折促销分子生物学试剂全系列产品,恭候您的咨询选购重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)促销。
温馨提示:不可用于临床ZL。