特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
北京百奥莱博专业生产销*(代"售")北京现货重组小鼠白介素IL-33(白细胞介素33)折扣价,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:北京现货重组小鼠白介素IL-33(白细胞介素33)折扣价
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Mouse Interleukin-33
编号:JN0385
本品由我们的大肠杆菌表达系统制备,目的基因编码的Ser109-Ile266表达纯化而来。
IL-33质量控制:>95%(还原性SDS-PAGE)。
IL-33制剂:冻干品
IL-33保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-33复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-33:
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up‑regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL‑1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1. BindingIL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.
欲咨询购买北京现货重组小鼠白介素IL-33(白细胞介素33)折扣价,请致电北京百奥莱博科技有限公司,为您提供最全面周到的产品服务,除此之外,我公司正在促销以下产品:
·重组人PDCD1(PD-1)(CD279)
编号:JN1526
英文名称:Recombinant Human Programmed Cell Death Protein 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu25-Gln167在C端带有Fc标签。
PDCD1/PD-1/CD279质量控制:>95%(还原性SDS-PAGE)
PDCD1/PD-1/CD279制剂:冻干品
PDCD1/PD-1/CD279保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
PDCD1/PD-1/CD279复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于PDCD1/PD-1/CD279:
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.
北京现货重组小鼠白介素IL-33(白细胞介素33)折扣价关键词:重组小鼠白介素IL-33,重组小鼠白细胞介素33,重组小鼠白介素IL-33蛋白,JN0385,重组白介素IL-33
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我公司正在打折促销分子生物学试剂全系列产品,恭候您的咨询选购北京现货重组小鼠白介素IL-33(白细胞介素33)折扣价。
温馨提示:不可用于临床ZL。