重组人载脂蛋白A1(ApoA1) 分子生物学试剂

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、YL及其他非科研用途。

北京百奥莱博专业生产供应重组人载脂蛋白A1(ApoA1) 分子生物学试剂，我公司销*(代"售")全品类的分子生物学试剂，价格优惠，欢迎广大科研工作者垂询订购。

名称：重组人载脂蛋白A1(ApoA1) 分子生物学试剂
编号：JN1200
英文名：Recombinant Human Apolipoprotein A-I
品Pai：百奥莱博
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Arg19-Gln267在C端含有His标签。

Apolipoprotein A-I/ApoA1质量控制：＞95%(还原性SDS-PAGE)

Apolipoprotein A-I/ApoA1制剂：冻干品

Apolipoprotein A-I/ApoA1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Apolipoprotein A-I/ApoA1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Apolipoprotein A-I/ApoA1：
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. In addition, ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.

欲了解更多重组人载脂蛋白A1(ApoA1) 分子生物学试剂的品Pai、产地、价格及说明书等产品信息，请致电北京百奥莱博科技有限公司，我们将竭诚为您服务，另外，以下产品正在火爆促销:
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重组人载脂蛋白A1(ApoA1) 分子生物学试剂关键词：重组人载脂蛋白A1,重组载脂蛋白A1,JN1200,重组人ApoA1,重组人载脂蛋白A1蛋白


·重组人IMPDH2(次黄嘌呤单核苷酸脱*酶)
编号：JN1058
英文名称：Recombinant Human Inosine-5-monophosphate dehydrogenase 2
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Phe514在N端含有His标签。

IMPDH2质量控制：＞95%(还原性SDS-PAGE)

IMPDH2制剂：液体

IMPDH2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于IMPDH2：
IMPDH2 is a cytosolic enzyme which belongs to the IMPDH/GMPR family. IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5- monophosphate. IMPDH2 is consequently involved in maintaining cellular guanine deoxy- and ribonucleotide pools required for DNA and RNA synthesis. In addition, IMPDH1 and IMPDH2 are targets for the important immunosuppressive drug, mycophenolic acid (MPA).


重组人载脂蛋白A1(ApoA1) 分子生物学试剂关键词：重组人载脂蛋白A1,重组载脂蛋白A1,JN1200,重组人ApoA1,重组人载脂蛋白A1蛋白


·重组人PLA2G1B(IB型磷脂酶A2)
编号：JN1286
英文名称：Recombinant Human Phospholipase A2 Group IB
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala23-Ser148在C端含有His标签。

PLA2G1B质量控制：＞95%(还原性SDS-PAGE)

PLA2G1B制剂：液体

PLA2G1B保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于PLA2G1B：
Phospholipase A2(PLA2G1B) is a secreted protein which belongs to the phospholipase A2 family. It catalyzes the release of fatty acids from glycero-3-phosphocholines. It catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Sequences of pancreatic PLA2G1B enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Mice lacking in PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet. Oral supplementation of a diabetogenic diet with the PLA2G1B inhibitor methyl indoxam effectively suppresses diet-induced obesity and diabetes. PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes.

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