特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
北京百奥莱博主要从事生物试剂的生产和销*(代"售"),产品线涵盖重组人细胞周期蛋白依赖型激酶2(CDK2) 分子生物学试剂在内的分子生物学试剂产品,还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。
名称:重组人细胞周期蛋白依赖型激酶2(CDK2) 分子生物学试剂
规格:10μg|50μg|500μg|1mg
产地:国产|进口
品Pai:百奥莱博
英文名:Recombinant Human Cyclin-Dependent Kinase 2
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Leu298在N端含有His标签。
CDK2质量控制:>95%(还原性SDS-PAGE)
CDK2制剂:液体
CDK2保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于CDK2:
Cyclin-dependent kinase 2 (CDK2) belongs to the cyclin-dependent kinase of Ser/Thr protein kinase. CDK2 acts as a catalytic subunit of the cyclin dependent kinase complex, whose activity is restricted to the G1-S phage of the cell cycle, it is essential for the G1/S transition. The kinase activity of CDK2 can be regulated by the association with a cyclin subunit, its phosphorylation state and CDK inhibitors. The activation of the CDK2/cyclin complex requires the phosphorylation of Thr160 and the dephosphorylation of Try14 and Tyr15. The inhibition of CDK2-cyclin complex can also be attributed to association with p27Kip1 and p21Waf1/Cip1. The activation of CDK2 has been shown to be necessary for apoptosis of quiescent cells, such as neurons, thymocytes and endothelial cells.
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重组人细胞周期蛋白依赖型激酶2(CDK2) 分子生物学试剂正在火爆,除此之外,为您推荐下别产品:
·重组人补体C1q和肿瘤坏死因子相关蛋白1(C1QTNF1)
编号:JN0442
英文名称:Recombinant Human Complement C1q and Tumor Necrosis Factor-Related Protein 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Arg26-Pro281在C端含有His标签。
C1QTNF1质量控制:>95%(还原性SDS-PAGE)
C1QTNF1制剂:冻干品
C1QTNF1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
C1QTNF1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于C1QTNF1:
C1QTNF1 is a secreted protein,contains 1 C1q domain and 1 collagen-like domain. C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms. C1QTNF1 is a novel adipokine, providing a significant framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. C1QTNF1 increases the production of aldosterone. C1QTNF1 is vastly expressed in obese subjects as well as up-regulated in hypertensive patients, C1QTNF1 is identified molecular link between obesity and hypertension. C1QTNF1 expression may be associated with a low-grade chronic inflammation status in adipose tissues.
重组人细胞周期蛋白依赖型激酶2(CDK2) 分子生物学试剂关键词:重组细胞周期蛋白依赖型激酶2,JN1986,重组人CDK2,重组人细胞周期蛋白依赖型激酶2蛋白
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