重组人趋化因子CCL26(Eotaxin-3) 分子生物学试剂

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、YL及其他非科研用途。

北京百奥莱博专业生产销*(代"售")重组人趋化因子CCL26(Eotaxin-3) 分子生物学试剂，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组人趋化因子CCL26(Eotaxin-3) 分子生物学试剂
编号：JN0305
英文名：Recombinant Human C-C Motif Chemokine 26
品Pai：百奥莱博
规格：10μg|50μg|500μg|1mg
产地：国产|进口
本品由我们的大肠杆菌表达系统制备，目的基因编码的Thr24-Leu94表达纯化而来。

CCL26/Eotaxin-3质量控制：＞95%(还原性SDS-PAGE)。

CCL26/Eotaxin-3制剂：液体

CCL26/Eotaxin-3保存：
收到后请置于-20℃，可稳定保存6个月，避免反复冻融。

关于CCL26/Eotaxin-3：
Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively expressed in thymus, but only transiently expressed in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for CCL26 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant CCL26 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, CCL26 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. CCL26 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.

除重组人趋化因子CCL26(Eotaxin-3) 分子生物学试剂外，我公司正在打折促销以下产品：

·重组小鼠FcRn
编号：JN1453
英文名称：Recombinant Mouse IgG Fc fragment receptor transporter
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser22-Val301&Ile21-Met119在C端含有His标签。

FcRn质量控制：＞95%(还原性SDS-PAGE)

FcRn制剂：冻干品

FcRn保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

FcRn复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于FcRn：
FcRn complex consist of two subunits: IgG receptor FcRnlarge subunit p51(alpha chain) and Beta-2-microglobulin(Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).


重组人趋化因子CCL26(Eotaxin-3) 分子生物学试剂关键词：重组人趋化因子CCL26蛋白,重组人Eotaxin-3,重组趋化因子CCL26,JN0305

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重组人趋化因子CCL26(Eotaxin-3) 分子生物学试剂关键词：重组人趋化因子CCL26蛋白,重组人Eotaxin-3,重组趋化因子CCL26,JN0305

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