北京现货重组人LOXL2(类赖氨酰氧化酶2)(赖氨酰氧化酶样蛋白2)批发

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、YL及其他非科研用途。

北京百奥莱博专业生产供应北京现货重组人LOXL2(类赖*酰氧化酶2)(赖*酰氧化酶样蛋白2)批发，我公司销*(代"售")全品类的分子生物学试剂，价格优惠，欢迎广大科研工作者垂询订购。

名称：北京现货重组人LOXL2(类赖*酰氧化酶2)(赖*酰氧化酶样蛋白2)批发
品Pai：百奥莱博
英文名：Recombinant Human Lysyl Oxidase Homolog 2
产地：国产|进口
编号：JN1654
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln26-Gln774在C端带Avi-His标签。

LOXL2质量控制：＞95%(还原性SDS-PAGE)

LOXL2制剂：液体

LOXL2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于LOXL2：
Lysyl oxidase homolog 2 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity. The N-terminus is poorly conserved and may imp*(代"a")rt additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels. LOXL2 is an enzyme that is up-regulated in several types of cancer and is associated with a poorer prognosis. LOXL2 changes the structure of histonesand thus changes the shape of the cells, making it easier for the cancer cells to metastasize.

更多有关北京现货重组人LOXL2(类赖*酰氧化酶2)(赖*酰氧化酶样蛋白2)批发的价格及使用说明等，请联系我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组人SCARB2
编号：JN1844
英文名称：Recombinant Human Scavenger Receptor Class B Member 2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg27-Thr432在C端含有His标签。

SCARB2质量控制：＞95%(还原性SDS-PAGE)

SCARB2制剂：冻干品

SCARB2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

SCARB2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于SCARB2：
Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal comp*(代"a")rtment. The protein deficiency in mice was reported to imp*(代"a")ir cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. In addition, SCARB2 also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.


北京现货重组人LOXL2(类赖*酰氧化酶2)(赖*酰氧化酶样蛋白2)批发关键词：JN1654,重组人类赖*酰氧化酶2,重组人赖*酰氧化酶样蛋白2,重组人LOXL2蛋白


·重组人TIMP-2(金属蛋白酶2组织YZ剂)
编号：JN1694
英文名称：Recombinant Human Tissue Inhibitor of Metalloproteinases 2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Cys27-Pro220在C端含有His标签。

TIMP-2质量控制：＞95%(还原性SDS-PAGE)

TIMP-2制剂：冻干品

TIMP-2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TIMP-2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TIMP-2：
Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.


北京现货重组人LOXL2(类赖*酰氧化酶2)(赖*酰氧化酶样蛋白2)批发关键词：JN1654,重组人类赖*酰氧化酶2,重组人赖*酰氧化酶样蛋白2,重组人LOXL2蛋白


·重组小鼠IL-12
编号：JN1491
英文名称：Recombinant Mouse Interleukin-12
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met23-Ser335&Arg23-Ala215表达纯化得来。

IL-12质量控制：＞95%(还原性SDS-PAGE)

IL-12制剂：冻干品

IL-12保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IL-12复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IL-12：
Mouse IL-12 is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. Human and mouse IL‑12 share 70% and 60% amino acid sequence identity in their p40 and p35 subunits, respectively. While mouse IL‑12 is active on both human and mouse cells, human IL‑12 is not active on murine cells. It is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-γ. T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes.IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.

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