品PaiThermo Scientific SIA (succinimidyl iodoacetate) 50 mg 西安瑞禧生物代理商
品PaiThermo Scientific SIA (succinimidyl iodoacetate) 50 mg 西安瑞禧生物代理商
品PaiThermo Scientific SIA (succinimidyl iodoacetate) 50 mg 西安瑞禧生物代理商
品PaiThermo Scientific SIA (succinimidyl iodoacetate) 50 mg 西安瑞禧生物代理商
Thermo Scientific Pierce SIA is a very short (1.5 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.
Features of SIA:
•
Reactive groups: NHS ester and iodoacetyl
•
Reactive toward: amino and sulfhydryl groups
• Shortest sulfhydryl-reactive and amine-reactive heterobifunctional crosslinker available; compare to SIAB
• NHS ester reacts with primary amines at pH 7-9 to form a stable amide bond
• Iodoacetyl group reacts with sulfhydryl groups at pH > 7.5 to form stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
英文别名:Iodoacetic Acid N-Succinimidyl Ester;N-SucciniMidyl Iodoacetate;(2,5-dioxopyrrolidin-1-yl) 2-iodoacetate;N-(Iodoacetoxy)succinimide;N-Succinimidyl iodoacetate(SIA);CAS号:39028-27-8分子式:C6H6INO4分子量:283.02100精确质量:282.93400PSA:63.68000Product References:
Crosslinker Application Guide -- search for recent literature references for this product
For Research Use Only. Not for use in diagnostic procedures.
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