SIA (succinimidyl iodoacetate) 货号: 22349 Thermo Fisher的代理商

SIA (succinimidyl iodoacetate)   货号: 22349 Thermo Fisher的代理商
SIA (succinimidyl iodoacetate)   货号: 22349 Thermo Fisher的代理商
SIA (succinimidyl iodoacetate)   货号: 22349 Thermo Fisher的代理商
SIA (succinimidyl iodoacetate)   货号: 22349 Thermo Fisher的代理商

Thermo Scientific Pierce SIA is a very short (1.5 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.

Features of SIA:

• Reactive groups: NHS ester and iodoacetyl
• Reactive toward: amino and sulfhydryl groups
• Shortest sulfhydryl-reactive and amine-reactive heterobifunctional crosslinker available; compare to SIAB
• NHS ester reacts with primary amines at pH 7-9 to form a stable amide bond
• Iodoacetyl group reacts with sulfhydryl groups at pH > 7.5 to form stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
For Research Use Only. Not for use in diagnostic procedures.

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