JN0798型重组人核糖核酸酶3(Rnase 3)供应

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、YL及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖JN0798型重组人核糖核酸酶3(Rnase 3)供应在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：JN0798型重组人核糖核酸酶3(Rnase 3)供应
编号：JN0798
规格：10μg|50μg|500μg|1mg
品Pai：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg28-Ile160在C端含有His标签。

Rnase 3质量控制：＞95%(还原性SDS-PAGE)

Rnase 3制剂：液体

Rnase 3保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Rnase 3：
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

关于JN0798型重组人核糖核酸酶3(Rnase 3)供应的更详细说明，请致电我公司咨询，我们将以最饱满的热情为您提供解答，此外，我公司专业供应下列产品：

·重组人白介素IL-12(白细胞介素12)
编号：JN0399
英文名称：Recombinant Human Interleukin-12
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Arg23-Ser219&Ile23-Ser328表达纯化而来。

IL-12质量控制：＞95%(还原性SDS-PAGE)。

IL-12制剂：冻干品

IL-12保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-12复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-12：
IL-12 is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit.Human and mouse IL‑12 share 70% and 60% amino acid sequence identity in their p40 and p35 subunits, respectively. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-γ. T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.


JN0798型重组人核糖核酸酶3(Rnase 3)供应关键词：重组人Rnase 3,重组人核糖核酸酶3蛋白,JN0798,重组核糖核酸酶3


·重组小鼠Havcr2(Tim-3)
编号：JN1422
英文名称：Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu22-Ala193在C端含有His标签。

Havcr2/Tim-3质量控制：＞95%(还原性SDS-PAGE)

Havcr2/Tim-3制剂：冻干品

Havcr2/Tim-3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Havcr2/Tim-3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Havcr2/Tim-3：
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.


JN0798型重组人核糖核酸酶3(Rnase 3)供应关键词：重组人Rnase 3,重组人核糖核酸酶3蛋白,JN0798,重组核糖核酸酶3


·重组人NCR3(天然细胞毒性触发受体3)
编号：JN0538
英文名称：Recombinant Human Natural Cytotoxicity Triggering Receptor 3
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu19-Thr138在C端含有His标签。

NCR3质量控制：＞95%(还原性SDS-PAGE)

NCR3制剂：冻干品

NCR3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

NCR3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于NCR3：
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.

我公司正在火爆促销分子生物学试剂系列产品，欢迎您的垂询选购JN0798型重组人核糖核酸酶3(Rnase 3)供应。