内毒素:Less than 1.0 EU per μg by the LAL method.
纯度:>95% as determined by SDS-PAGE.
活性:Measured by its binding ability in a functional ELISA. Immobilized Recombinant Protein G, His Tag (Cat. No. RPG-S3140) at 2 μg/mL (100 μL/well) can bind Biotinylated Human IgG1 Fc, Avitag (Cat. No. IG1-H8213) with a linear range of 0.013-0.512 μg/mL (Routinely tested).
产品背景:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
产品描述:This protein carries an Avi tag at the C-terminus. The protein has a calculated MW of 28.4 kDa. The protein migrates as 36-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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http://www.acrobiosystems.cn/P1118-Biotinylated_Human_IgG1_Fc_protein_Avitag.html
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