重组丙型肝炎病毒NS5B/HCV NS5B_详细资料

产品信息 重组丙型肝炎病毒NS5B/HCV NS5B 产品编号:HCV-269产品名称:重组丙型肝炎病毒NS5B/HCV NS5B产品规格:100ug/500ug/1mg Catalogue Number HCV-269 Introduction HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the hosts immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). Description The E.coli derived recombinant protein contains the full length of the NS5B immunodominant regions and fused to a 6xHis tag at C-Terminus. Purification Method HCV NS3 Genotype-1a protein was purified by proprietary chromatographic technique. Purity Protein is >95% pure as determined by SDS-PAGE. Formulation 1.5M urea, 25mM Tris-HCl pH 8.0, 0.2% Triton-X and 50% Glycerol. Stability HCV NS5B although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. Specificity Immunoreactive with sera of HCV-infected individuals. Applications HCV NS5B antigen in ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems. Usage ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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Catalogue Number	HCV-269
Introduction	HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the hosts immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Description	The E.coli derived recombinant protein contains the full length of the NS5B immunodominant regions and fused to a 6xHis tag at C-Terminus.
Purification Method	HCV NS3 Genotype-1a protein was purified by proprietary chromatographic technique.
Purity	Protein is >95% pure as determined by SDS-PAGE.
Formulation	1.5M urea, 25mM Tris-HCl pH 8.0, 0.2% Triton-X and 50% Glycerol.
Stability	HCV NS5B although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Specificity	Immunoreactive with sera of HCV-infected individuals.
Applications	HCV NS5B antigen in ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
Usage	ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.