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NMS-P118 is a potent, orally available, and highly selective PARP-1 Inhibitor for cancer therapy with an IC50of 0.04 μM in HeLa cell.
NMS-P118 is a potent, orally available, and highly selective PARP-1 Inhibitor for cancer therapy with an IC50of 0.04 μM in HeLa cell.
Naquotinib( ASP8273) is an orally available, irreversible, third-generation, mutant-selective EGFR inhibitor with IC50 of 8-33 nM toward EGFR mutants, IC50 of 230 nM for WT EGFR.
BAY 1143572 is a highly selective, potent and orally available inhibitor of PTEFb/CDK9; inhibits the proliferation of AML cell lines with a median IC50 of 385 nM.
CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.
美仑,MB4288,Akt Inhibitor VIII, Isozyme-Selective,Akt Inhibitor VIII, Isozyme-Selective
Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM; is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more).
Abcam优势服务 货号:ab146011,Selective Hsp27 inhibitor. Microtubule inhibitor.
AZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor.
DDP-38003 dihydrochloride is an novel, orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with an IC50 of 84 nM.
Selective JAK3 inhibitor 1,1443235-95-7
Potent, selective GSK3 inhibitor
Selective STAT3 inhibitor
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