Human ICAM-1/重组人细胞间粘附分子-1

Human ICAM-1/重组人细胞间粘附分子-1
产品编号:100-341 产品名称: Human ICAM-1/重组人细胞间粘附分子-1 产品规格:50μg
Description: ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1. Monomeric glycosylated ICAM-1 migrates at an apparent molecular weight of approximately 72.0-80.0 kDa by SDS-PAGE analysis under reducing conditions.
Source: CHO cells
Molecular Weight: 72-80 kDa
Purity: 98 % (SDS-PAGE, HPLC)
Endotoxin level/内毒素水平: < 0.1 ng per ug of ICAM-1
Stabilizer: none
Formulation: lyophilized
Biological Activity: Data not available!
Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted ICAM-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C.
Avoid repeated freeze-thaw cycles.
Usage: Human ICAM-1 is offered for research use. Not for drug use. Not for human use.