Cynomolgus Glypican 3 / GPC3 Protein

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>85% as determined by SDS-PAGE.

活性:
Measured by its binding ability in a functional ELISA. Immobilized Human FGF basic, Tag Free (Catalog # BFF-H4117) at 0.5 μg/mL (100 μL/well) can bind Cynomolgus Glypican 3, His Tag (Catalog # GP3-C5225) with a linear range of 1-20 ng/mL.

产品背景:
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.

产品描述:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 62.7 kDa. The protein migrates as 66-150 kDa, 40 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
 SDS-PAGE
Cynomolgus Glypican 3 / GPC3, His Tag on SDS-PAGE  under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.