Recombinant Human Proinsulin C-Peptide Analogue (rHuProinsulin C-Peptide Analogue)

规格编号：C640027-0050
概述：Proinsulin, a molecular weight of 8 kDa to 10 kDa, is a precursor of insulin. It has minimum hormonal activity and is converted to insulin by removal of the connecting C-peptide. Mature insulin has 35 fewer amino acids; 4 are removed altogether and the remaining 31 form the C-peptide. The C-peptide is abstracted from the center of the proinsulin sequence; the two other ends (the B chain and A chain) remain connected by disulfide bonds. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle and glycogen synthesis in liver.
使用说明：This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE
Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Purity > 95 % by SDS-PAGE and HPLC analyses.
Source Escherichia coli.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Endotoxin Less than 0.1 EU/μg of rHuProinsulin C-Peptide Analogue as determined by LAL method.
AA Sequence RREAEDLQVG QVELGGGPGA GSLQPLALEG SLQKR