Stemolecule™ SB431542 (10 mg)_详细资料

产品信息

供应商： Stemgent 英文名： Stemolecule™ SB431542 (10 mg) 保质期： 1年保存条件： 4℃ 规格： 10 mg

Stemgent 致力于通过提供由一些世界DJ干细胞科研人员所开发的专有试剂和工具促进干细胞科学的发展。
Stemgent提供独特的小分子Stemolecules可用于研究和调整干细胞在自我更新和多能干细胞的分化过程中的信号转导，而且能用于IPS重编程和诱导IPS产生。Stemolecules经过细胞毒性检测，一般用来增强IPS细胞的产生和维持多能干细胞的多能状态。妙通（上海）生物科技有限公司作为Stemgent在ZG的代理商，感恩回馈新老客户，现就Stemolecules部分小分子产品，7折火热促销！！！

促销时间：2015.6.1-2015.7.31

产品订购请电联：4008-217-320
产品特点：
1.JJ的细胞穿透性，只需加入培养基即可使用；
2.低抗原性；
3.经过严格的干细胞毒性测试；
4.具有高纯度＞98%。

Stemolecule™ SB431542
Stemolecule™ SB431542是TGF-β1活化受体激酶的YZ剂。是ALK-4, -5 ，-7的潜在YZ剂，SB431542YZ内在的活化剂以及TGF-β信号，而不影响应用ALK-1, -2, -3, -6的BMP信号。据报道，1μM浓度的SB431542能刺激来源于胚胎干细胞的内胚层细胞的增殖，分化和形成。

Product Overview
SB431542 is an inhibitor of the transforming growth factor-beta 1 (TGF-β1) activin receptor-like kinases (ALKs). It is a selective and potent inhibitor of ALK-4, -5 and -7. SB431542 inhibits endogenous activin and TGF-β signaling without affecting more divergent BMP signaling utilizing ALK-1, -2, -3, and -6^1,2. SB431542 stimulates proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells³.
Product Specifications
Size
：5 mg (Cat. No. 04-0010)
10 mg (Cat. No. 04-0010-10)
Alternate Name
：4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Chemical Formula
：C₂₂H₁₆N₄O₃
Molecular Weight
：384.4
CAS Number
：301836-41-9 (anhydrous)
Purity
：Greater than 98% by HPLC analysis
Formulation
：White solid
Solubility
：Reconstitute in DMSO to the desired concentration. For reconstitution instructions please reference product specifications sheet.
Storage and Stability
：Store powder at 4°C protected from light. Following reconstitution, store aliquots at -20°C. Stock solutions are stable for 6 months when stored as directed.
Quality Control
：The purity of SB431542 was determined by HPLC analysis. The accurate mass was determined by mass spectrometry. Cellular toxicity of SB431542 was tested on mouse embryonic stem cells.

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Stemolecule™ SB431542 (10 mg)

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