DNA依赖蛋白激酶催化亚基（Anti-DNAPK/PRKDC）抗体【现货促销】

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产品名称：DNA依赖蛋白激酶催化亚基（Anti-DNAPK/PRKDC）抗体【现货促销】 

中文名称：DNA依赖蛋白激酶催化亚基抗体
英文名称：Anti-DNAPK/PRKDC
产品编号：BYK-1359R
产品别名：DNA-dependent protein kinase catalytic subunit; DNA-PK catalytic subunit; DNA-PKcs; DNPK1; p460; PRKDC; HYRC; HYRC1; Variant; DNAPK; DNAPK catalytic subunit; p350; PRKDC; Protein Kinase DNA Activated Catalytic Polypeptide; XRCC 7; XRCC7; PRKDC_HUMAN.

本公司另供应“DNA依赖蛋白激酶催化亚基抗体”的标记有：Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC.
产品规格：100ug/200ug
产品浓度： 1mg/1ml
抗体来源：兔源、鼠源、其他
克 隆：单克隆抗体、多克隆抗体
抗体类型：一抗
性 状： 冻干粉或液体
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

DNA依赖蛋白激酶催化亚基（Anti-DNAPK/PRKDC）抗体【现货促销】技术说明，产品推荐，由于篇幅原因，更多信息请：

Anti-CT-R/FITC  荧光素标记降钙素受体抗体IgG
Anti-CSMD1/FITC  荧光素标记抑癌基因CSMD1抗体IgG
Anti-CTBP1/FITC  荧光素标记C端结合蛋白1抗体IgG
Anti-Cx40/FITC  荧光素标记间隙连接蛋白40抗体IgG
Anti-Cx43/FITC  荧光素标记Connexin-43蛋白抗体IgG
Anti-CX45/FITC  荧光素标记间隙连接蛋白45抗体IgG
Anti-CXCL4/PF-4/FITC  荧光素标记血小板因子4抗体IgG
Anti-CXCL5/ENA-78/FITC  荧光素标记上皮中性粒细胞活化肽78抗体IgG
Anti-GCP-2/CXCL6 /FITC  荧光素标记抗粒细胞趋化蛋白2抗体IgG
Anti-CXCL7/NAP-2/PPBP/FITC  荧光素标记中性粒细胞趋化蛋白2抗体IgG
Anti-CXCL9/MIG/CMK/FITC  荧光素标记γ干扰素诱导单核细胞因子抗体IgG

Anti-CTSC/PALS/DPP-I/FITC  荧光素标记组织蛋白酶C抗体IgG
Anti-CTn1/FITC  荧光素标记心肌肌钙蛋白抗体IgG
Anti-CTNNAL1/FITC  荧光素标记粘附分子相关蛋白a1抗体IgG
Anti-CULLIN/Cdc53/CUL/SCFCdc4 /FITC  荧光素标记CULLIN抗体IgG
Anti-Cx26/FITC  荧光素标记整合素样间隙连接蛋白26抗体IgG
anti-CXCL10/IP-10 /FITC  荧光素标记CXCL10趋化因子10/干扰素诱导蛋白10抗体IgG
Anti-CXCL11/ITAC/FITC  荧光素标记干扰素诱导T细胞趋化因子抗体IgG
Anti-SDF-1/CXCL12 /FITC  荧光素标记基质细胞衍生因子－1抗体IgG
Anti-CXCL13/BLC-1/FITC  荧光素标记B-淋巴细胞趋化因子抗体IgG
Anti-CXCL14/FITC  荧光素标记CXC趋化因子14抗体IgG
Anti-CXCL15/Lungkine/FITC  荧光素标记趋化因子CXCL15体IgG
Anti-CXCL16/FITC  荧光素标记CXC趋化因子16抗体IgG

产品介绍：

Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining （NHEJ） required for double-strand break （DSB） repair and V（D）J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V（D）J recombination by activation of the hairpin endonuclease artemis （DCLRE1C）. The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of omeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.